| Date | Competition | Opponents | Venue | Score | Goalscorers | Att | Rep | Vid |
|---|---|---|---|---|---|---|---|---|
| 12/08/2000 | Div 1 | STOCKPORT COUNTY | H | 1-3 | Butters | 9429 |  |  |
| 19/08/2000 | Div 1 | Tranmere Rovers | A | 2-3 | Asaba,Southall(p) | 8355 | | |
| 22/08/2000 | FLC1 | TORQUAY UTD | H | 2-0 | Asaba,Thomson | 2743 | | |
| 25/08/2000 | Div 1 | PORTSMOUTH | H | 1-1 | Thomson | 8741 | | |
| 28/08/2000 | Div 1 | Burnley | A | 1-1 | Asaba | 15611 | | |
| 02/09/2000 | Div 1 | WOLVERHAMPTON WANDERERS | H | 1-0 | Lewis | 10017 | | |
| 09/09/2000 | Div 1 | Grimsby Town | A | 0-1 | 4512 | | | |
| 13/09/2000 | Div 1 | Queens Park Rangers | A | 2-2 | Asaba,Hessenthaler | 10655 | | |
| 16/09/2000 | Div 1 | HUDDERSFIELD TOWN | H | 2-1 | Butters,Smith | 8503 | | |
| 20/09/2000 | FLC2 | Manchester City | A | 1-1 | Smith | 17408 | | |
| 23/09/2000 | Div 1 | Fulham | A | 0-3 | 13032 | | | |
| 26/09/2000 | FLC2 | MANCHESTER CITY | H | 2-4 (aet) | Thomson(2) | 6520 | | |
| 30/09/2000 | Div 1 | SHEFFIELD WEDNESDAY | H | 2-0 | Butters,Thomson | 9099 | | |
| 06/10/2000 | Div 1 | BOLTON WANDERERS | H | 2-2 | Smith,Onuora | 9311 | | |
| 14/10/2000 | Div 1 | Wimbledon | A | 4-4 | Thomson(2),Saunders,Asaba | 9030 | | |
| 17/10/2000 | Div 1 | Watford | A | 0-0 | 12356 | | ||
| 21/10/2000 | Div 1 | BARNSLEY | H | 0-0 | 9030 | | ||
| 25/10/2000 | Div 1 | Birmingham City | A | 0-1 | 26044 | | ||
| 28/10/2000 | Div 1 | CREWE ALEXANDRA | H | 0-1 | 8347 | | ||
| 04/11/2000 | Div 1 | Sheffield Utd | A | 2-1 | Smith,Thomson | 14028 | | |
| 12/11/2000 | Div 1 | NOTTINGHAM FOREST | H | 1-3 | Onuora | 9884 | | |
| 18/11/2000 | Div 1 | West Bromwich Albion | A | 1-3 | King | 16410 | | |
| 25/11/2000 | Div 1 | Blackburn Rovers | A | 2-1 | Hessenthaler,OG | 18061 | | |
| 09/12/2000 | Div 1 | Norwich City | A | 0-1 | 16725 | | | |
| 26/12/2000 | Div 1 | CRYSTAL PALACE | H | 4-1 | Asaba(3),Onuora | 10518 | | |
| 01/01/2001 | Div 1 | Portsmouth | A | 0-0 | 14526 | | ||
| 06/01/2001 | FAC3 | Bournemouth | A | 3-2 | Hope,Hessenthaler,Shaw | 7403 | |